THX-UltraII
Let me try to answer 
It is part of your script (setting's values):
multinum=5
multiden=2
algo=13
block=false
ml=0
search=4
sadml=0
sadgamma=1
blend=true
dist=2
pel=1
sharp=0
Recalc=0
blkh=32
blkv=32
overlap=0
overlapv=0
wid_den=1
hei_den=1
It is right values. But you can change some of it (marked with bold font) to get less artifacts. I reproduced your profile settings.
You can:
1. Change Search radius to 1 pixel. It makes dynamics of motion a little shorter and less waves-artifacts. It is easier to CPU.
2. Change Block overlapping to 0.25 of block. It makes motions in frame more coherence. It is heavier to CPU.
3. Change Bad areas artifacts suppression to Normal or Below Normal. It adds mask above artifacts areas but makes smoothness of such areas less noticeable. It is heavier to CPU.
4. Change SVP-shader to 2. Simple bidirectional. It will make new frames maximally sharp. Best choice for anime. It is easier to CPU or GPU if accelerated.
5. Change Framerate change to 1m or 2m. It will leave more source frames in video hence less noticeable artifacts on new frames. The equability of motion will be a little broken. It is easier to CPU or GPU if accelerated.
Good luck
